广东牙病防治2011，Vol.19Issue(6)：312-315,4.
牙周非手术治疗对2型糖尿病伴慢性牙周炎患者牙周炎症控制及血清C反应蛋白水平影响的研究
Effects of Non-surgical Treatment on Control of Periodontitis and Serum C-reactive Protein in Type 2 Diabetic Patients with Chronic Periodontitis
摘要
Abstract
Objective To explore the effect of non-surgical therapy on control of periodontitis and serum CRP level in type 2 diabetic patients with chronic periodonfitis. Methods One hundred and thirty-five type 2 diabetic patients with chronic periodontitis were randomly assigned into two groups. Clinic index (PD, AL) and serum CRP level were examined in both groups before and after periodontal therapy. Results At the baseline, the mean PD emerged as a significant predictor for elevated CRP ( P ＜ 0.05 ). In correlation analysis, CRP was associated with mean PD ( r = 0. 230, P =0. 009 ), but not with mean AL( P ＞ 0. 05 ). In treatment group, reduction of PD was (0.48 ± 0. 45) mm, while reduction of AL was (0.32 ±0.51 ) mm, and reduction of CRP was (1.56 ±5.03) mg/L, there were statistically significant differences in PD ( P ＜0.05 ), AL ( P ＜0.05) and serum CRP level ( P ＜0.05 ) before and after non-surgical periodontal treatment. However, there was no significant difference ( P ＞0.05 ) of PD, AL and serum CRP level in control group during the time. There was significant difference ( P ＜ 0. 05 ) of mean PD between treatment group and control group,however, but no significant difference in mean AL and serum CRP level ( P ＞ 0. 05 ) between treatment group and control group. Conclusion Non-surgical periodontal treatment was helpful in improving periodontal status in type 2 diabetic patients with chronic periodontitis, but the evidence was not enough to support that non-surgical periodontal treatment could improve serum CRP level in these patients.关键词
2型糖尿病/慢性牙周炎/牙周非手术治疗/牙周指数/C反应蛋白Key words
Type 2 diabetes mellitus/ Chronic periodontitis/ Non-surgical periodontal therapy/ Periodontal index/ C-reactive protein分类
医药卫生引用本文复制引用
戚威娟,陈蕾,刘芳,章锦才..牙周非手术治疗对2型糖尿病伴慢性牙周炎患者牙周炎症控制及血清C反应蛋白水平影响的研究[J].广东牙病防治,2011,19(6):312-315,4.基金项目
广东省科技计划项目(2010B031600117) （2010B031600117）
