云南农业大学学报2011，Vol.26Issue(3)：317-322,339,7.DOI:10.3969/j.issn.1004-390X(n).2011.03.006
乌金猪与长白猪肝脏脂肪代谢相关基因mRNA表达水平的比较研究
Comparative Studies on Level mRNA Expression Profile of Lipid Metabolism Related Genes from Wujin and Landrace Pigs
摘要
Abstract
Liver mRNA expression level of nine lipid metabolism related genes from Wujin and landrace pigs was investigated and compared for providing theoretical basis to further study the mechanism of lipid metabolism in different breeds.The results revealed that the mRNA expressions of fatty acid synthase (FAS) , ACC, SREBP and ME genes in liver of Wujin pigs were dramatically higher than those of land-race pigs (P ＜0.01 or P ＜0.05), the expressions of CPT-1 and ACOX genes in liver of Wujin pigs were lower than landrace pigs (P ＜0.01 or P ＜0.05) , and Wujin pigs expressed higher level of ApoB gene in liver (P＜0.05).However, the expressions of DGAT-1 and PPARa genes were no significantly different in liver of this two breeds (P ＞ 0.05 ).These results suggested that the expression of genes related to fat synthesis and fatty acids transportation was higher and that of stearolysis genes was lower in liver of Wujin pigs, which leaded to the higher capacity of fat synthesis in liver tissue.关键词
脂类代谢/基因表达/肝脏/猪Key words
lipid metabolism/ genes expression/ liver/ pigs分类
农业科技引用本文复制引用
韩茜,赵素梅,黄英,张永云,李卫真,高士争..乌金猪与长白猪肝脏脂肪代谢相关基因mRNA表达水平的比较研究[J].云南农业大学学报,2011,26(3):317-322,339,7.基金项目
"973"前期研究专项(2007CB116201) （2007CB116201）
云南省自然科学基金重点项目(2005C0008Z). （2005C0008Z）
