中国全科医学2011，Vol.14Issue(20)：2269-2270,2.
老年高血压晨峰与血清脑钠肽的相关性及其转归研究
A Correlation and Outcome Research of Hypertension Morning Peak and Serum BNP in Elder Patients with Essential Hypertension
邱治芬 1许庆党 2谭洪勇3
作者信息
- 1. 277606山东省微山县,枣庄矿务局滕南医院内科
- 2. 山东省济宁市疾病控制中心
- 3. 山东省济宁医学院临床学院
- 折叠
摘要
Abstract
Objective To explore the correlations between hypertension morning peak and serum BNP in elder patients with essential hypertension, and to observe the outcomes of those patients with hypertension morning peak within one year.Methods A total of 69 elder patients with newly diagnosed essential hypertension and hypertension morning peak diagnosed by ambulatory blood pressure monitoring were enrolled as the observation group, with another 42 randomly selected aged newly diagnosed essential hypertension cases without hypertension morning peak enrolled as control group.Serum BNP levels and LVMI were compared between the two groups.Incidence rate of cardio - cerebrovascular events in both groups were also observed.Results Both Serum BNP levels and LVMI of the observation group were higher than those of the control group ( t = 6.177, P ＜ 0.001; t = 7.093, P ＜ 0.001 ).Incidence rate for cardio 鈥?cerebrovascular events ( myocardial infarction, unstable angina, sudden cardiac death, heart failure, malignant arrhythmia and stroke ) were higher among elder patients with hypertension morning peak than among the control group ( x2 = 12- 585, P = 0.0004 ).Conclusion Disfunction of the serum BNP may be involved in the emergence of hypertension morning peak in elder patients, which in turn intensifies the damage of target organs, resulting in more cardio 鈥?cerebrovascular events.关键词
高血压晨峰/脑钠肽/动态血压监测/靶器官损害Key words
Hypertension morning peak/ Brain natriuretic peptide/ Ambulatory blood pressure monitoring/ Target -organ damage分类
医药卫生引用本文复制引用
邱治芬,许庆党,谭洪勇..老年高血压晨峰与血清脑钠肽的相关性及其转归研究[J].中国全科医学,2011,14(20):2269-2270,2.
