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吸烟致冠状动脉慢血流现象研究

范小明 吕安康 沈卫峰 马晓晔 吴祁红 杨二丽 张瑞岩 张奇

内科理论与实践2011,Vol.6Issue(3):200-203,4.
内科理论与实践2011,Vol.6Issue(3):200-203,4.

吸烟致冠状动脉慢血流现象研究

Cigarette smoking causes slowing of coronary blood flow

范小明 1吕安康 1沈卫峰 1马晓晔 1吴祁红 1杨二丽 1张瑞岩 1张奇1

作者信息

  • 1. 上海交通大学医学院附属瑞金医院心内科,上海,200025
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摘要

Abstract

Objective To study the influence of cigarette smoking on coronary blood flow in patients with normal coronary artery angiography. Methods One hundred and twenty three patients with normal coronary artery angiography were divided into smoking group (57 patients) and non-smoking group (66 patients) according to their cigarette smoking status. Thrombolysis in myocardial infarction (TIMI) frame counts of left anterior descending artery, left circumflex artery and right coronary artery and average TIMI frame counts of overall major coronary arteries were calculated. Analyzed the slowing of coronary blood flow and their related risk factors. Results TIMI frame counts of left anterior descending artery ( 41.43±15.29 vs 36.5±11.75, P<0.05), left circumflex artery (29.48±9.95 vs 23.43±12.54, P<0.05), right coronary artery (25.33±10.92 vs 20.63±11.28, P<0.05) and average TIMI frame counts of overall major coronary arteries (31.23±13.11 vs 27.12±9.68, P<0.05) in smoking group were significantly higher than those in non-smoking group. Smoking, obesity,diabetes mellitus and hyperlipidemia were the independent risk factors of slowing of coronary blood flow. Conclusions In smokers, coronary blood flow was impaired despite the morphology of coronary artery remains in normal range.

关键词

吸烟/冠状动脉/心肌梗死溶栓/血流帧数/慢血流

Key words

Smoking/ Coronary artery/ Thrombolysis in myocardial infarction frame count/ Frame count/Slowing blood flow

分类

医药卫生

引用本文复制引用

范小明,吕安康,沈卫峰,马晓晔,吴祁红,杨二丽,张瑞岩,张奇..吸烟致冠状动脉慢血流现象研究[J].内科理论与实践,2011,6(3):200-203,4.

内科理论与实践

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1673-6087

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