安徽医科大学学报2011，Vol.46Issue(9)：953-956,4.
下肢深静脉血栓形成药物治疗的临床分析
The clinical analysis of medication in lower extremity deep venous thrombosis
骆广义 1宋海屏1
作者信息
- 1. 安徽医科大学第一附属医院血管外科,合肥,230022
- 折叠
摘要
Abstract
Objective To discuss the thrombolytic agents in the treatment of lower extremity deep venous thrombo
sis( LDVT ). Methods We summarized a retrospective analysis of 379 patients with LDVT treated in our hospital
who were combined therapy with thrombolysis, anticoagulation and anti-platelet adhesion. We divided the 379 cases
into three groups:acute stage( ≤3 d ), subacute stage( 3 ～ 14 d ) and chronic stage( ＞ 14 d ) group according to
disease period. Each group was further divided into two sub-groups according to therapeutic protocol:thrombolysis
plus anti-coagulation, anti-platelet adhesion and anticoagulation plus anti-platelet adhesion. Results Patients in a
cute stage had the best clinical efficacy of thrombolysis plus anticoagulation and anti-platelet adhesion. The clinical
efficacy of thrombolysis plus anticoagulation and anti-platelet adhesion was more effectual than anticoagulation plus
anti-platelet adhesion to patients in subacute and chronic stage( P ＜0. 01 ). The 158 LDVT patients of postopera
tions had better effect with thrombolysis plus anticoagulation and anti-platelet adhesion than anticoagulation plus an
ti-platelet adhesion( P ＜0. 01 ) and the complications was indifference. Conclusion Combined therapy with throm
bolysis, anticoagulation, and anti-platelet adhesion therapy is primary treatment of LDVT. Thrombolysis plus anti
coagulation and anti-platelet adhesion treatment is effective for patients in non-acute stage,and which is an effective
and safe method for postoperative LDVT under the tight monitoring.关键词
下肢/静脉血栓形成/药物疗法/血栓溶解疗法Key words
lower extremity /venous thrombosis/drug therapy/ thrombolysis therapy 分类
医药卫生引用本文复制引用
骆广义,宋海屏..下肢深静脉血栓形成药物治疗的临床分析[J].安徽医科大学学报,2011,46(9):953-956,4.
