安徽农业科学2011，Vol.39Issue(14)：8276-8278,3.
花脸香蘑发酵物的体外抗氧化及抗肿瘤活性研究
In Vitro Antioxidative and Antitumor Activities of Fermentions of Lepista sordida ( Schumach. :Fr. ) Singer
摘要
Abstract
[ Objective ] To determine the in vitro antioxidative and antitumor activities of the fermentions from Lepista sordida( Schumach. :Fr. ) Singer. [ Method] Extracted with different solvents, the antioxidant and antitumor activities of each secondary metabolites of Lepista sordida (Schumach. :Fr. ) Singer were determined by DPPH method and MTT method,respectively. [ Result] The ethyl acetone (EA) extracts of the solid fermentations exhibited the highest activity in DPPH radical inhibition assays, followed by the ethyl acetone (EA) extracts of the liquid fermentations. The ethyl acetone (EA) extracts of the liquid fermentations showed the highest antitumor activity and thel1C50 value was about 50 μg/ml on the human cervix epitheloid carcinoma cell lines(Hela). The extracts of the mycelia also showed stronger antioxidative and antitumor activities. [ Conclusion]The above -mentioned results provided new scientific basis for further study and exploitation of Lepista sordida( Schumach.:Fr. ) Singer.关键词
花脸香蘑[Lepista sordida(Schumach.:Fr.)Singer]/次生代谢物质/DPPH/MTTKey words
Lepista sordida ( Schumach. :Fr. ) Singer/ Secondary metabolites/ DPPH/ MTT分类
农业科技引用本文复制引用
陈湘莲,李泰辉,沈亚恒..花脸香蘑发酵物的体外抗氧化及抗肿瘤活性研究[J].安徽农业科学,2011,39(14):8276-8278,3.基金项目
广东省科技计划项目(2005B33302005) （2005B33302005）
广东省自然科学基金项目(E05202480). （E05202480）
