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针刺治疗急性脑出血机制研究的现状分析

王凡 王海桥 东贵荣

针刺研究2011,Vol.36Issue(2):145-149,5.
针刺研究2011,Vol.36Issue(2):145-149,5.

针刺治疗急性脑出血机制研究的现状分析

Progress of Researches on Mechanism of Acupuncture Therapy Underlying Improvement of Acute Cerebral Hemorrhage

王凡 1王海桥 1东贵荣1

作者信息

  • 1. 上海中医药大学附属岳阳中西医结合医院,上海,201203
  • 折叠

摘要

Abstract

In the present paper, the authors review the progress of researches on the mechanism of acupuncture therapy underlying improvement of acute cerebral hemorrhage from experimental studies and research methods. The effects of acupuncture intervention mainly involve 1 ) lessening inflammatory reactions, 2) reducing impairment of free radicals and excitatory amino acids on cerebral neurons, 3) balancing release of vascular bioactive substances to increase regional cerebral blood flow, and 4) promoting repair and regeneration of the neural tissue, etc. In regard to the research methods, many new biological techniques such as biological molecular approaches, neuro-cellular chemical methods, reverse transcription-polymerase chain reaction (RT-PCR) or quantitative real time-PCR, situ hybridization, western blotting, electron microscope, etc., have been extensively applied to researches on the underlying mechanism of acupuncture therapy for cerebral infarction. In addition, the authors also pointed out that in spite of achieving some bigger progresses in experimental studies, most of the results basically reflect static, isolated and regional changes rather than dynamic and whole body changes. For this reason, more vivo research techniques and noninvasive research methods are highly recommended to be used in the future research on the underlying mechanisms of acupuncture therapy for acute cerebral ischemia.

关键词

针刺疗法/脑出血/作用机制/综述

Key words

Acupuncture therapy/ Cerebral hemorrhage/ Research mechanism/ Review

分类

医药卫生

引用本文复制引用

王凡,王海桥,东贵荣..针刺治疗急性脑出血机制研究的现状分析[J].针刺研究,2011,36(2):145-149,5.

基金项目

国家自然科学基金课题"百会穴透刺捻转补泻时空效应特性规律的现代研究"(No.90709030) (No.90709030)

针刺研究

OACSCDCSTPCDMEDLINE

1000-0607

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