中国药房2011,Vol.22Issue(24):2279-2280,2.
还原型谷胱甘肽辅助治疗小儿急性肾小球肾炎的疗效观察
Efficacy Observation of Adjunctive Therapy of Reduced Glutathione for Pediatric Acute Glomerulonephritis
李雪松 1杨龙 1邹顺1
作者信息
- 1. 昆明医学院第一附属医院,昆明市,650032
- 折叠
摘要
Abstract
OBJECTIVE: To observe the therapeutic efficacy of adjunctive therapy of reduced glutathione for pediatric acute glomemlonephritis. METHODS: Children with acute glomerulonephritis receiving conventional treatment were randomly divided into treatment group (27 cases)and control group (26 cases). The control group with convertional therapy, treatment group were additionally given adjunctive therapy of reduced glutathione 12 mg·kg-1 ·d-1. Both of 2 groups were treated for 2 weeks. RESULTS:Comparedwith control group, the recovery time of oedema, urinary production and blood pressure of treatment group were decreased significantly (P<0.05). After 2 week-treatment,the serum urea nitrogen, 24 h urine protein quantitation and excretory rate of urine erythrocyte in treatment group were lower than in control group significantly(P<0.05). There wasn'n ADR appeared in 2 groups. CONCLUSION: Reduced glutathione is benefit for the recovery of pediatric acute glomerulonephritis.关键词
还原型谷胱甘肽/急性肾小球肾炎/儿童Key words
Reduced glutathione/ Acute glomemlonephritis/ Children分类
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李雪松,杨龙,邹顺..还原型谷胱甘肽辅助治疗小儿急性肾小球肾炎的疗效观察[J].中国药房,2011,22(24):2279-2280,2.