重庆医学2011，Vol.40Issue(21)：2087-2088,2093,3.DOI:10.3969/j.issn.1671-8348.2011.21.003
天麻干预酒精诱发胃动力障碍的实验研究
The experimental research of gastrodia elata for white wine-induced dynamic dysfunction of stomach
摘要
Abstract
Objective to explore the effects and mechanisms of gastrodia elata to treat the white wine induced dynamic dysfunction of stomach in dogs. Methods 7 beagles underwent four different regimens in sequence. The blank section were performed with 100 mL saline intravenously and the implantation of gastric tube. The other three sections were the same as the blank session except that the corresponding management. The white wine section with commercially available white wine ( 57％ ethanol, 7 mL/kg),the gastrodia elata section were the same as the white wine except the gastrodia elata (5 g/kg) ,the L-Arg section were the same as the gastrodia elata except the intravenous L-Arg (150 mg/kg). All were examined the concentration of the nitrogen oxide and motilin before and after meal for 30 minutes as well as recorded the gastric waves 1 hours both in fasting and postprandial conditions. Resuits white wine slowed the gastric emptying with the decrease of NO and motilin. The gastrodia elata improved the gastric empty ing with the increase of motilin, And L-Arg increased NO but motilin, which was similar to the gastrodia elata for improving the gastric emptying. Conclusion The gastrodia elata can improve the white wine induced dysfunction of the gastric emptying, which relate to the increase of the motilin. And NO do not play a major role in this event.关键词
天麻/胃动力/一氧化氮/胃动素Key words
gastrodia elata/ gastric motility/ nitric oxide/ motilin引用本文复制引用
张云东,杨杰,韩兴权,万登敏..天麻干预酒精诱发胃动力障碍的实验研究[J].重庆医学,2011,40(21):2087-2088,2093,3.基金项目
安顺市科技计划基金资助项目(20082023). （20082023）
