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骨髓间充质干细胞的相关迁移机制

徐世红 谢兴文

中国组织工程研究与临床康复2011,Vol.15Issue(19):3573-3576,4.
中国组织工程研究与临床康复2011,Vol.15Issue(19):3573-3576,4.DOI:10.3969/j.issn.1673-8225.2011.19.037

骨髓间充质干细胞的相关迁移机制

Migration mechanism of bone marrow mesenchymal stem cells

徐世红 1谢兴文2

作者信息

  • 1. 甘肃中医学院,甘肃省兰州市,730000
  • 2. 甘肃省中医院,甘肃省兰州市,730020
  • 折叠

摘要

Abstract

BACKGROUND: Based on the multiple differentiation potential, bone marrow mesenchymal stem cells (BMSCs) migrating to the injury site greatly promote patient’s rehabilitation.OBJECTIVE: To investigate the mechanism of cytokines and inflammatory factors to promote the migration of BMSCs based on analysis of related literature.METHODS: The first author retrieved China National knowledge Infrastructure and PubMed datebases for concering articles .The key words were “BMSCs, chemotactic factor, migration” in Chinese and English. A total of 68 articles were retrieved primarily by computer, and 23 articles were finally included for review according to inclusion criteria.RESULTS AND CONCLUSION: BMSCs have a strong differentiation potential and play a huge assistance role in the clinical treatment. At the same time, because BMSCs are easy and simple to harvest and culture in vitro, studies concerning the proliferation, differentiation and migration of BMSCs are hot points. The intervention function of related cell factors urges BMSCs to strength migration.

关键词

迁移/骨髓间充质干细胞/细胞因子/中药/综述文献

分类

医药卫生

引用本文复制引用

徐世红,谢兴文..骨髓间充质干细胞的相关迁移机制[J].中国组织工程研究与临床康复,2011,15(19):3573-3576,4.

基金项目

国家自然科学基金项目(81060299). (81060299)

中国组织工程研究与临床康复

OACSCDCSTPCD

2095-4344

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