中国临床药理学杂志2011，Vol.27Issue(5)：348-351,4.
Mohnarin2009年度报告:非发酵革兰阴性杆菌耐药监测
Mohnarin 2009 report:surveillance of antimicrobial resistance in nonfermenting gram-negative bacteria in China
李耘 1吕媛1
作者信息
- 1. 北京大学,第一医院,临床药理研究所,北京100034
- 折叠
摘要
Abstract
Objective To investigate the antimicrobial resistance of nonfermenting gram - negative bacteria in China in 2009. Methods All the clinical stains of gram- negative nonfermenters were isolated and the susceptibility tests of the isolates were performed by 114 tertiary hospitals around China from 1 st Jan. 2009 to 31 st Dec. 2009. The susceptibilities of isolates to antimicrobial agents were determined by using CLSI (2009) guideline and the susceptibility data were processed with WHONET 5.5 software by centre laboratory. Results In 2009, a total of 54566 nonfermenting gram- negative bacteria susceptibility data were obtained. Among all the isolates, P. aeruginosa (23525 strains) outnumbered the other bacteria, accounting for 43. 1％, followed by A. baumannii (19801 strains, 36. 3％ ). Against P. aeruginosa, colistin, amikacin, piperacillin/tazobactam, meropenem and tobramycin were the only agents to which ＞ 70％ of isolates were susceptible. No antibiotics, except colistin (93.2％) and minocycline (65.4％), were active more than 55％ against of A. baumannii. Resistance rates of carbarpenem against A. baumannii were about 47％. Conclusion Multidrug resistance nonfermenting gram- negative bacterial has been a worldwide challenge for healthcare management. Enhanced antimicrobial resistance surveillance need to be strengthened to block the further development and spread of resistant bacteria, promote judicious antimicrobial use.关键词
非发酵革兰阴性杆菌/细菌耐药性Key words
nonfermenting gram - negative/ resistance of bacteria分类
医药卫生引用本文复制引用
李耘,吕媛..Mohnarin2009年度报告:非发酵革兰阴性杆菌耐药监测[J].中国临床药理学杂志,2011,27(5):348-351,4.
