中国临床医学影像杂志2011，Vol.22Issue(5)：316-320,5.
MR弥散加权成像在延迟期强化的肝脏恶性肿瘤与肝血管瘤鉴别诊断中的应用
Potential of diffusion-weighted MR in differentiating primary malignant liver tumor enhanced in delayed phase and cavernous hemangioma
摘要
Abstract
Objective: To investigate the potential of diffusion-weighted MR imaging(DWI) in differentiating primary malignant liver tumor enhanced in delayed phase on contrast-enhanced MRI and cavernous hemangioma.Materials and Methods:Diffusion weighted MR scans were performed using an 1.5T MR scanner at a b value of 500s/mm2 in 32 cases of focal hepatic lesions enhanced in delayed phase on contrast-enhanced MRI, including 11 cavernous hemangiomas and 21 primary malignant tumors (9 hepatocellular carcinomas, 12 cholangiocarcinomas).Quantitative analysis was performed using the regions of interest(ROI) settled on these tumors.The mean ADC values of cavernous hemangioma, hepatocellular carcinoma and cholangiocarcinoma were calculated and analyzed by student t tests respectively.P value of less than 0.05 was considered to indicate statistical significance.Results: The mean ADC value of hepatocellular carcinoma [(1.28±0.46)×10-3]and cholangiocarcinoma [(1.61±0.38)×10-3]were significantly lower than that of cavernous hemangioma [(2.85±0.89)×10-3](t=4.780, P=0.000; t=3.7025, P=0.001 respectively).However, there were no significant differences of mean ADC values between hepatocellular carcinoma and cholangiocarcinoma (t=1.8008, P=0.088).Conclusion: DWI might be helpful to differentiate primary malignant liver tumor enhanced in delayed phase on contrast-enhanced MRI from cavernous hemangioma.关键词
肝肿瘤/血管瘤/磁共振成像/诊断,鉴别Key words
Liver neoplasms/ Hemangioma/ Magnetic resonance imaging/ Diagnosis, differential分类
医药卫生引用本文复制引用
白若冰,郭启勇,石喻,卢再鸣,杨京川,孙宝海..MR弥散加权成像在延迟期强化的肝脏恶性肿瘤与肝血管瘤鉴别诊断中的应用[J].中国临床医学影像杂志,2011,22(5):316-320,5.基金项目
国家自然科学基金项目(30670593). （30670593）
