安徽农业科学2011，Vol.39Issue(10)：5738-5740,5818,4.
茶多酚与银杏叶提取物联用对人乳腺癌细胞增殖的影响
Combined Effect of Tea polyphenols and Ginkgo Biloba Extract on Proliferation of Human Breast Cancer Cells
徐泽平 1蒋琳兰2
作者信息
- 1. 华南理工大学生物科学与工程学院,广东广州,510006
- 2. 广州军区广州总医院药剂科,广东广州,510010
- 折叠
摘要
Abstract
[ Objective ] To observe the combined effects of Tea polyphenols and Ginkgo biloba extract on proliferation of human breast cancer cell line MDA-MB-231. [ Method ] Effects of tea polyphenols,Ginkgo biloba extract and their combination on human breast cancer cell line MDA-MB231 were detected by MTT method,besides,cell morphological analysis was employed to examine the morphological changes of MDA-MB-231 in all test groups. [ Result ] The inhibition rate of Ginkgo biloba extract combined with tea polyphenols at low concentration( 10,20 μg/ml)was the highest ,and the combined group could cause synergies in a certain range; in addition,human breast cancer cell line MDA-MB-231 was in poor state and had weak refraction rate in combined group,adherent cells was shrunk and became round by comparison with tea polyphenols group,Ginkgo biloba extract group and control group. [ Conclusion ] Ginkgo biloba extract at low concentration had little inhibitory effect on human breast cancer cell line MDA-MB-231. Tea polyphenols and combination group can inhibit the growth of MDA-MB-231 ,and the combination effects of tea polyphenols and Ginkgo biloba extract are synergistic in a certain range only.关键词
茶多酚/银杏叶提取物/联合应用/人乳腺癌细胞Key words
Tea polyphenols/Ginkgo biloba Extract/Combination/Human breast cancer eell分类
农业科技引用本文复制引用
徐泽平,蒋琳兰..茶多酚与银杏叶提取物联用对人乳腺癌细胞增殖的影响[J].安徽农业科学,2011,39(10):5738-5740,5818,4.
