重庆医学2011,Vol.40Issue(18):1778-1780,3.DOI:10.3969/j.issn.1671-8348.2011.18.004
不同质子泵抑制剂治疗反流性食管炎的疗效分析
Analysis of therapeutic effects of different proton pump inhibitors in treatment of reflux esophagitis
摘要
Abstract
Objective To compare the cure rates of reflux esophagitis treated with different doses of proton pump inhibitors.Methods The abstracts and full articles of prospective randomized controlled clinical trial were collect, relevant data were extracted,and the fixed effects model were employed to perform analysis. Results The cure rate of short term treatment(4 weeks) of reflux esophagitis with esophagitis 40 mg was higher than that with omeprazole 20 mg(RR:1. 14;95 %CI:1. 10~1.18). Comparision of the cure rats of reflux esophagitis treated with omeprazole, pantoprazole, lansoprazole and rabeprazole showed no significant difference. Conclusion The curative effect of esomeprazole for the short term treatment of reflux esophagitis is superior to that of pantoprazole, lansoprazole and rabeprazole.关键词
质子泵/食管炎/埃索美拉唑/奥美拉唑Key words
proton pumps/ esophagitis/ esomeprazole/ omeprazole引用本文复制引用
夏春生,刘华蓉,达世平,沈微..不同质子泵抑制剂治疗反流性食管炎的疗效分析[J].重庆医学,2011,40(18):1778-1780,3.