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四角蛤蜊糖胺聚糖的分离纯化及功能活性研究

袁春营 崔青曼 孙会芳 孙晓朋

安徽农业科学2011,Vol.39Issue(10):5882-5884,5886,4.
安徽农业科学2011,Vol.39Issue(10):5882-5884,5886,4.

四角蛤蜊糖胺聚糖的分离纯化及功能活性研究

Study on Purification and Functional Activity of Glycosaminoglycan from Mactra quadrangularis

袁春营 1崔青曼 1孙会芳 1孙晓朋1

作者信息

  • 1. 天津市海洋资源与化学重点实验室,天津科技大学海洋科学与工程学院,天津,300457
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摘要

Abstract

[Objective] To study the purification and function of Glycosaminoglycan(GAG) from Mactra quadrangularis. [Method] GAG was isolated from soft parts of Mactra quadrangularis,and was purified. Functions of purified GAG were analyzed. [ Result]The purity of GAG gained from the soft parts of Mactra quadrangularis reached 95.03% ,after 2 purification. Hydroxyl radical and superoxide anion radica could be scavenged by GAG,but the scavenging capacity of GAG was weaker than Vc. Anticoagulant effect of GAG was weaker than heparin. [ Conclusion] GAG had strong anticoagulant effect and scavenging capavity to hydroxyl radical and superoxide anion radical.

关键词

四角蛤蜊/糖胺聚糖/纯化/功能

Key words

Mactra quadrangularis/Glycosaminoglycan/Purification/Functions

分类

轻工纺织

引用本文复制引用

袁春营,崔青曼,孙会芳,孙晓朋..四角蛤蜊糖胺聚糖的分离纯化及功能活性研究[J].安徽农业科学,2011,39(10):5882-5884,5886,4.

基金项目

天津市塘洁区科委基金项目(2007XQ16-09). (2007XQ16-09)

安徽农业科学

0517-6611

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