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新型β-环糊精制备及性能的实验研究

胡茗 赵峰 孟舒献 田刚

现代检验医学杂志2011,Vol.26Issue(3):53-55,3.
现代检验医学杂志2011,Vol.26Issue(3):53-55,3.DOI:10.3969/j.issn.1671-7414.2011.03.019

新型β-环糊精制备及性能的实验研究

Study on the Preparation and Fuction of New Beta-cyclodextrin

胡茗 1赵峰 2孟舒献 3田刚4

作者信息

  • 1. 天津公安医院药剂科,天津,300040
  • 2. 新疆自治区中医院检验科,乌鲁木齐,830000
  • 3. 天津大学化学系,天津,300070
  • 4. 天津公安医院检验科,天津,300040
  • 折叠

摘要

Abstract

Objective To explore the new beta-cyclodextrin preparation and fuction and to develop the drug of healing hypertension. Methods On the condition of alkality and crosslinking proverbially,to obtain macromolecular cyclodextrin having the capability of swelling and no-solution. To determin the solubility and adsorbability of new beta-cyclodextrin by sodium cholate experiment. Results The largest adsorption quantity of the new type beta-cyclodextrin was 68. 07± 0. 55 mg/g under 50℃ ,meanwhile 72. 05±0. 48 mg/g under 60 ℃. However,obtaining the polymer by the method of general crosslinking was partial diffluent,and trimmed adsorption quantity was about 63. 01 ±1. 08 mg/g under 60℃ . Conclusion The new beta-cyclodextrin has widely applied perspective.

关键词

β-环糊精/性能/制备/交联

Key words

beta-cyclodextrin / fuction / preparation / crosslinking

分类

医药卫生

引用本文复制引用

胡茗,赵峰,孟舒献,田刚..新型β-环糊精制备及性能的实验研究[J].现代检验医学杂志,2011,26(3):53-55,3.

基金项目

天津市公安局科技基金资助项目(GA200704). (GA200704)

现代检验医学杂志

OACSTPCD

1671-7414

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