现代检验医学杂志2011，Vol.26Issue(3)：91-95,5.DOI:10.3969/j.issn.1671-7414.2011.03.031
铜绿假单胞菌耐药机制研究进展
Research Progress of Resistance Mechanisms of Pseudomonas Aeruginosa
摘要
Abstract
Pseudomonas aeruginosa is a common clinical conditioned pathogens. The extensive and irrational use of antimicrobial agents ,makes the resistance of Pstudomonas aeruginosa becoming stronger. There has been a lot of multidrug resistant strains which makes the clinical treatment great difficult. Resistance mechanisms of Pseudomonas aeruginosa is very complex. This review summarized the resistance mechanisms of the barrier of outer membrane permeability,the change of action targets,the formation of inactivated enzyme,the formation of biofilm and active efflux pump system.关键词
铜绿假单胞菌/耐药机制/β-内酰胺酶/生物膜/主动外排泵Key words
Pseudomonas aeruginosa / resistance mechanisms / β-lactamases / biofilmaaive efflux pump分类
医药卫生引用本文复制引用
林冬玲,陈茶,曾建明..铜绿假单胞菌耐药机制研究进展[J].现代检验医学杂志,2011,26(3):91-95,5.基金项目
本研究受国家自然科学基金资助(项目编号:81071397). （项目编号:81071397）
