老年医学与保健2011，Vol.17Issue(3)：167-169,3.DOI:10.3969/j.issn.1008-8296.2011-03-13
泛耐药菌感染老年患者的细菌耐药性分析及其临床意义
Analysis of drug resistance and its clinical significance in the elderly patients infected with pan-drug-resistant bacteria
摘要
Abstract
Objective To analyze the drug resistance and its clinical significance in the elderly patients infected with pan-drug-resistant bacteria. Methods 302 elderly patients infected with Pseudomonas aeruginosa and Acinetobacter baumannii were studied retrospectively. Bacterial identification and drug susceptibility were identified from the specimens in patients (sputum, blood, urine, bile, wounds, etc.). According to the experimental results all patients were divided into two groups: pan-drug-resistant bacteria infection (PI) and non- pan-drug-resistant bacteria infection (NPI) groups. Cure rate and mortality were observed and compared. The underlying diseases and drug use were assessed . Results 34 cases were detected to be infected with pan-drug-resistant bacteria and 268 cases were detected with non- pan-drug-resistant bacteria from the 302 elderly patients. The cure rate of the PI group was significantly lower than that of the NPI group (35 ％ vs 75 .4 ％ , P ＜ 0.01), mortality of the PI group was markedly higher than that of NPI group (18 ％ vs 3 .7 ％ , P＜ 0.01) .Conclusion The drug resistance of pan-drug-resistant bacteria greatly harms elderly patients, witch should be solved by taking effective measures.关键词
老年/泛耐药菌/细菌耐药性Key words
Elderly/ Pan-drug-resistant bacteria/ Bacterial drug resistance分类
医药卫生引用本文复制引用
方毅,庞立峰,过静,赵虎..泛耐药菌感染老年患者的细菌耐药性分析及其临床意义[J].老年医学与保健,2011,17(3):167-169,3.基金项目
复旦大学附属华东医院院级课题(H-646) （H-646）
