老年医学与保健2011，Vol.17Issue(3)：176-178,3.DOI:10.3969/j.issn.1008-8296.2011-03-16
糖尿病前期人群血脂谱变化特点及其意义
The characteristic of serum lipoprotein spectrum in the pre-diabetes people
摘要
Abstract
Objective To investigate the characteristic and changes of serum lipoprotein spectrum in the prediabetes people. Methods According to oral glucose tolerance test (OGTT), 2 212 examinees aged 20 ～ 75 years were classified into the following three groups: normal glucose tolerance (NGT), pre-diabetes and diabetes. The fasting lipids and clinical data among three groups were compared. Results Compared with those of NGT group, subjects in pre-diabetes group had higher levels in total cholesterol (TC) (5.18±1.15 vs 4.96±1.04) mmol/ L, and low density lipoprotein-cholesterol (LDL-C) (3.17±0.93 vs 3.00±0.93) (P＜0.01), but high density lipoprotein-cholesterol (HDL-C) decreased (1.27±0.34 vs l.30±0.29) (P＜0.05). There were no differences in total triglyceride (TG) between NGT and pre-diabetes groups (1.73±1.19 vs 1.67±4.70, P＞0.05). The dyslipidemia was more obvious in the diabetes groups than the pre-diabetes group. Age, hypertension, BMI, waist circumference and blood pressure were obviously abnormal in the pre-diabetes group, compared with the NGT group, excepted diabetes family history. Conclusions Diabetic dyslipidemia exists in the pre-diabetes people. The therapy for dyslipidemia may be beneficial in the pre-diabetes people, and should be considered routinely for all the pre-diabetes and the diabetic patients.关键词
糖尿病前期/血脂异常Key words
Pre-diabetes/ Dyslipidemia分类
医药卫生引用本文复制引用
吴丹荣,时立新,严征,庄惠君,贡明贤..糖尿病前期人群血脂谱变化特点及其意义[J].老年医学与保健,2011,17(3):176-178,3.基金项目
贵阳医学院青年科学基金项目(K2007-86) （K2007-86）
