中德临床肿瘤学杂志（英文版）2011，Vol.10Issue(8)：459-461,3.DOI:10.1007/s10330-011-0850-3
Bag-1蛋白表达与胃交响癌临床病理因素关系的研究
The relationship between Bag-1 and gastric cancer clinicopathologic characteristic
摘要
Abstract
Objective: The aim of our study was to investigate Bcl-2 antanogene-1 (Bag-1) expressions in gastric cancer and evaluate their clinical significance. Methods: Bag-1 expressions were studied by the immunohistochemical streptavidinperosidase (S-P) method in 62 samples of gastric cancer tissues, 11 normal gastric tissues, and their clinical significance was analyzed. Results: The positive rate of Bag-1 expression in the gastric carcinoma tissues was 41.94% (26/62), while it was 9.09% (1/11) in the normal gastric tissues (P = 0.046). Though Bag-1 was positively related to the tumour pathological grade, lymph node metastasis and prognosis (P < 0.05), it was not related to the sex, age, location, tumour diameter, depth of invasion (P > 0.05). Conclusion: There are over expression of Bag-1 gene protein in gastric cancer, it is significance in prognosis of gastric cancer.关键词
gastric cancer/immunohistochemistry/prognosisKey words
gastric cancer/immunohistochemistry/prognosis引用本文复制引用
Jiyuan Yang,Zhiqiang Cai,Wei Du,Junchuan Li,Tingxuan Chen,Yunhua Xu..Bag-1蛋白表达与胃交响癌临床病理因素关系的研究[J].中德临床肿瘤学杂志（英文版）,2011,10(8):459-461,3.基金项目
Supported by a grant from Hubei Province Office of Education (No.D20101310). （No.D20101310）
