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癌性恶病质与细胞因子相关性的临床研究

何文杰 任宏轩 王羽丰

四川医学2011,Vol.32Issue(5):674-676,3.
四川医学2011,Vol.32Issue(5):674-676,3.

癌性恶病质与细胞因子相关性的临床研究

Relationship of cytokine level with cancer cachexia and its clinical research

何文杰 1任宏轩 1王羽丰1

作者信息

  • 1. 云南省肿瘤医院干部医疗科,云南,昆明,650118
  • 折叠

摘要

Abstract

Objective To study the expression of cytokine in the cancer cachexia patients and to discuss the relationship with cancer cachexia. Methods To compare the IL-1 、IL-6 、TNF-α、IFN-γ levels with 80 cases patients of cancer cachexia 、40 cases healthy people and 40 cases patients of non-cancer cachexia. To oral medroxyprogesterone with the 80 cases patients of cancer cachexia and give the nutritional support of four weeks. Four weeks later, to detect the levels of IL-1 、IL-6 、TNF-α IFN-γand compare with pre-treatment. Results Compared cancer cachexia group with non-cancer cachexia group and healthy group, the levels of IL-1 、IL-6 、TNF-α 、IFN-γ increased. P < 0. 05 , there were significances in statistics; The 80 cases patients of cancer cachexia through four weeks treated. the levels of IL-1 、IL-6 、TNF-α 、IFN-γ decreased. P < 0. 05 , there were significances in statistics. Conclusion Cytokines are relevant to the cancer cachexia and playing an important role.

关键词

癌性恶病质/细胞因子/相关性

Key words

cancer cachexia/ cytokine / relationship

分类

医药卫生

引用本文复制引用

何文杰,任宏轩,王羽丰..癌性恶病质与细胞因子相关性的临床研究[J].四川医学,2011,32(5):674-676,3.

四川医学

OACSTPCD

1004-0501

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