中国组织工程研究与临床康复2011，Vol.15Issue(25)：4661-4664,4.DOI:10.3969/j.issn.1673-8225.2011.25.025
脱蛋白松质骨作为异种骨移植材料的修复作用
Repair effect of deproteinised cancellous bone as xenogeneic bone graft material
摘要
Abstract
BACKGROUND: Unequal size, mutual communication, and open pore network structure can be seen in cancellous bone treated with deproteinization. Its inorganic component is hydroxyapatite, and the organic component is collagen, which has a good mechanical property and biocompatibility. It may be a new type of bone graft material.OBJECTIVE: To study the properties of xenogeneic deproteinised cancellous bone being carrier of bone tissue engineering in bone fusion.METHODS: Taking “xenogeneic deproteinised cancellous bone, bone fusion, carrier” in Chinese as search terms, the articles from January 1998 to December 2009 in VIP database, CNKI database, Pubmed database were retrieved by computer. The relevant literatures were included, the literature of irrelevant purpose and repetitive content were excluded, and 33 of them were involved for further analysis.RESULTS AND CONCLUSION: Compared with synthetic bone material, animal bones have similar biomaterial structure, modeling, excellent cell attachment, and cell growth and proliferation environment. However, the compatibility of bone tissue is poor, because of the differences in species when xenogeneic deproteinised cancellous bone transplantation, and gravis immune rejection, the key question is implantation of immune problems. How to overcome immunogenicity, xenogeneic deproteinised cancellous bone is a good carrier of bone tissue engineering, which can provide a stable environment for revascularization and differentiation of osteoblasts.关键词
异种脱蛋白松质骨/骨融合/载体/异种骨移植/综述文献分类
医药卫生引用本文复制引用
高春阳,姜宏春,金春明..脱蛋白松质骨作为异种骨移植材料的修复作用[J].中国组织工程研究与临床康复,2011,15(25):4661-4664,4.基金项目
牡丹江医学院科学技术研究项目(2010-27). （2010-27）
