中国组织工程研究与临床康复2011，Vol.15Issue(25)：4687-4690,4.DOI:10.3969/j.issn.1673-8225.2011.25.031
组织工程人工骨材料修复长骨节段性缺损的现状与展望
Tissue-engineered bone materials for repair of long bone segmental defects
摘要
Abstract
BACKGROUND: Bone graft, artificial substitute replacement, bone lengthening and other repair methods for long bone segmental defects have been used in clinic, but they have their own limitations.OBJECTIVE: To review and summarize the current methods of bone defect treatment, and to analyze the developmental prospect of the treatment for the long bone defect.METHODS: The first author searched PubMed Database and Chinese Medical Current Contents to retrieve articles about long bone defect repair published 2000-01 to 2010-12. The keywords were “bone defect, bone tissue engineering, artificial bone,bone transplantation, therapy” in English and Chinese. Older articles and repetitive studies were excluded.RESULTS AND CONCLUSION: Thirty-three articles were included in final analysis. Repair methods for long bone segmental defects include autogenous bone graft, allograft, bone lengthening, bone substitute transplantation. Tissue engineered bone to repair bone defects has become the hot topic nowadays, but there are many urgent questions to be solved. The tissue engineered bone is a promising means of treating bone defects.关键词
长骨节段性缺损/修复/生物材料/骨组织工程/人工骨/骨移植分类
医药卫生引用本文复制引用
李长庚,徐建强..组织工程人工骨材料修复长骨节段性缺损的现状与展望[J].中国组织工程研究与临床康复,2011,15(25):4687-4690,4.基金项目
全军医药卫生科研基金课题(06G018). （06G018）
