肿瘤防治研究2011，Vol.38Issue(3)：302-304,3.DOI:10.3971/j.issn.1000-8578.2011.03.016
荧光原位杂交在膀胱尿路上皮癌中的应用
Detection of Uroepithelium Carcinoma of Bladder by Fluorescence in situ Hybridization
摘要
Abstract
Objective To explore of clinical application of chromosome 3, 7, 17 and 9p21 combination probe to monitor urothelial carcinoma recurrence and to diagnose urothelial carcinoma. Methods Detect the urin-cells from the urina sanguinis and the tissue sections of patient who trouble epithelioma of bladder by FISH. Results The sensibility to monitor the recurrence of epithelioma of bladder is 87.50％ and the masculine rate is 78.85％ to diagnose epithelioma of bladder by FISH. The patient who was positive by FISH to be more easier to recurrent than who was negative after operation. Conclusion We can monitor the recrudescence of carcinoma of bladder effectively and anticipate the recrudescence after operation by using the FISH which can detect chromosome 3,7, 17 and 9p21 aberrations in urin-cells. Our finding indicates that FISH can be used in the tissue sections of bladder organization. Meanwhile, it can be used to assist the diagnosis of bladder carcinoma.关键词
荧光原位杂交/膀胱尿路上皮癌/染色体崎变分类
医药卫生引用本文复制引用
肖兰,杨继洲,康照利..荧光原位杂交在膀胱尿路上皮癌中的应用[J].肿瘤防治研究,2011,38(3):302-304,3.基金项目
湖北省科技厅研究与开发计划资助项目(2008BCZ003) （2008BCZ003）
