实用医学杂志2011，Vol.27Issue(10)：1737-1739,3.DOI:10.3969/j.issn.1006-5725.2011.10.010
肝脏CT灌注成像与门静脉压力相关性的动物实验研究
Correlation between hepatic CT perfusion imaging and portal vein pressure in normal Beagles
摘要
Abstract
Objective To evaluate the correlation between the parameters of spiral CT perfusion imaging and portal vein pressure in normal Beagles. Methods Twenty-four normal beagles were selected to receive hepatic spiral CT perfusion imaging. The parameters of hepatic perfusion , including blood flow (BF) , blood volume (BV) ,mean transit time ( MTT) , hepatic arterial fraction ( HAF) , hepatic arterial perfusion ( HAP) , and portal venous perfusion (PVP) , were calculated hy the method of deconvolution. The portal vein pressure was measured by glass column method in laparotomy surgery three days after CT imaging. Results Portal vein pressure of the beagles were ( 13.57 ± 1.15) cmH2O. Portal vein pressure was negatively correlated with the BF and PVP , but was positively correlated with HAF. PVP was the most significant parameter that correlated with portal vein pressure (r = -0.764,P＜0.05) , and their linear regression equation was Y = 16.507-0.037X. Conclusion CT perfusion imaging is a new non-invasive and eff'ective method for assessing portal vein pressure.关键词
门静脉压/体层摄影术,X线计算机/灌注/比格犬引用本文复制引用
林元为,陈伟建,张启瑜,梁盼,杨博洋..肝脏CT灌注成像与门静脉压力相关性的动物实验研究[J].实用医学杂志,2011,27(10):1737-1739,3.基金项目
浙江省外科学重中之重学科 （）
