实用医学杂志2011，Vol.27Issue(10)：1751-1753,3.DOI:10.3969/j.issn.1006-5725.2011.10.016
不同能量负荷对正常糖耐量人群GLP-1的影响
A preliminary study of GLP-1 secretion patterns and the effects of different loads in the normal glucose toleranc people
摘要
Abstract
Objective To investigate the secretion patterns of GLP-1 after two different loads (glucose and mixed meal) in the normal glucose tolerance(NGT) people. Methods After no energy intake for 12 hours, fourteen normal glucose tolerance subjects had height, weight, blood pressure, waist, hip circumference measurement at 8:00 a.m, Blood glucose, insulin and GLP-1 were taken at 0, 15, 30, 60, 90 and 120 minutes after glucose load or mixed meal load. Results (1) In NGT group , the secretion of GLP-1 was two-phased after glucose load. The first peak value of GLP-1 was at 15 minutes;and the second peak value was at 60 minutes. (2)There was no obvious peak value of GLP-1 after mixed neal. Conclusion In NGT group , the secretion of GLP-1 was two-phase after glucose load. There was no apparent peak of GLP-1 after mixed meal. The secretion patterns of GLP-1 in the NGT people is different after two different loads.关键词
正常糖耐量/肠促胰岛素/GLP-1引用本文复制引用
陈重,严励,傅晓莹,杨华章,邝建..不同能量负荷对正常糖耐量人群GLP-1的影响[J].实用医学杂志,2011,27(10):1751-1753,3.基金项目
广东省中医药局科研课题计划项目(编号:2009115) （编号:2009115）
广东省医学科研基金课题(编号:A2010027) （编号:A2010027）
广东省科技计划项目(编号:2010B031600171) （编号:2010B031600171）
