实用医学杂志2011，Vol.27Issue(10)：1767-1769,3.DOI:10.3969/j.issn.1006-5725.2011.10.022
脂联素及高敏C反应蛋白与原发性高血压合并痛风的关系
The relationship between adiponectin, high sensitivity C-reactive protein and essential hypertention plus gout
摘要
Abstract
Objective To investigate the changes of adiponectin (APN) and high sensitivity C-reactive protein (hs-CRP) in the treatment of essential hypertensive patients with gout, and to analyse the relationships between them. Methods The study enrolled 120 patients who visited the Affiliated Hospital of Guilin Medical College.These patients were divided into three groups: 60 cases in essential hypertension with gout group; 30 cases in essential hypertension group; 30 cases in gout group. And other 30 cases of healthy individuals served as control group. Serum APN was evaluated using enzyme-linked immunosorbent assay (ELISA),and plasma level of hs-CRP was assessed with immunoturbidimetry. Results The level of APN was significantly higher while the level of hs-CRP was significantly lower in patients of essential hypertension with gout after treatment; Negative correlations were found between APN and hs-CRP in essential hypertensive patients with gout group. Conclusion The level of APN decreased while hs-CRP increased as the blood pressure and uric acid decreased in the hypertensive patients with gout.关键词
高血压/痛风/高敏C反应蛋白/脂联素引用本文复制引用
莫新玲,王要鑫,谢福生,李全忠..脂联素及高敏C反应蛋白与原发性高血压合并痛风的关系[J].实用医学杂志,2011,27(10):1767-1769,3.基金项目
桂林市科学技术与应用开发项目(编号:20100128-7) （编号:20100128-7）
