中国临床药学杂志2011，Vol.20Issue(2)：111-113,3.
磷酸奥司他韦预防甲型H1N1流感时引起不良反应206例报道
Report of 206 cases of adverse drug reactions in using oseltamivir to prevent influenza A H1N1 influenza
董伟 1王艳彩1
作者信息
- 1. 公安海警学院医院内科,宁波,315801
- 折叠
摘要
Abstract
AIM To analyse the adverse drug reactions (ADRs) occurred in people who took oseltamivir phosphate to prevent influenza A H1N1 influenza. METHODS The ADRs of 2 978 cases who took oseltamivir phosphate 75 mg once daily for 7 d to prevent influenza A H1N1 influenza were recorded every day and 2 790 cases with intact data were carried out statistical analysis. RESULTS There were 206 cases of ADRs, with the total ADRs incidence rate of 7.38％. Cases with the main clinical manifestations of enteron symptoms such as diarrhea, nausea, and bellyache etc.were 157, with the incidence rate of 5.62％. The incidenec rate of ADRs was low in rash, otalgia, tachycardia, foreign body sensation of esophagus and nosebleed and insomnia etc. CONCLUSION The ADRs of oseltamivir phosphate in the prevention of influenza A HIN1 influenza mainly were enteron symptoms which do not affect the treatment in general. But if such symptoms as rash or tachyeardia occur, the drug should be immediately stopped and symptomatic treatment must be given.关键词
磷酸奥司他韦/甲型H1Nl流感/药物不良反应引用本文复制引用
董伟,王艳彩..磷酸奥司他韦预防甲型H1N1流感时引起不良反应206例报道[J].中国临床药学杂志,2011,20(2):111-113,3.
