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帕罗西汀联合奥氮平治疗抑郁症的临床效果和安全性分析

皇甫丽

国际医药卫生导报2011,Vol.17Issue(11):1368-1370,3.
国际医药卫生导报2011,Vol.17Issue(11):1368-1370,3.DOI:10.3760/cma.j.issn.1007-1245.2011.11.031

帕罗西汀联合奥氮平治疗抑郁症的临床效果和安全性分析

The clinical effect and safety of paroxetine combined with olanzapine used for therapy of depression

皇甫丽1

作者信息

  • 1. 510600,广州,广东药学院附属第一医院
  • 折叠

摘要

Abstract

Objective To explore the clinical effects and safety of using paroxetine and olanzapine to treat depression.Methods Selected 80 cases of patients with depression as studied object, and randomly divided them into experimental group and control group. Control group was treated with paroxetine; while experimental group was treated with paroxetine and olanzapine. Results (1) The efficiency rate and total effective rate in experimental group are significantly better than that in control group(x2=3.905, P < 0.05; x 2=4.507, P< 0.05 ). (2) There is no serious side-effect that happened in two groups, and the side-effect rates in two groups have no significant difference (x2=0.060, P > 0.05 ). Conclusions Using paroxetine and olanzapine to treat depression has better clinical effect, and the risk can be controlled, so it deserves to apply and prompt it on clinical work.

关键词

帕罗西汀/奥氮平/抑郁症

Key words

Paroxetine/Olanzapine/Depression

引用本文复制引用

皇甫丽..帕罗西汀联合奥氮平治疗抑郁症的临床效果和安全性分析[J].国际医药卫生导报,2011,17(11):1368-1370,3.

国际医药卫生导报

1007-1245

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