广西医学2011，Vol.33Issue(5)：533-535,3.
艾滋病合并播散性马尔尼菲青霉菌病预后因素分析
Prognostic Factors of Disseminated Penicilliosis Marneffei in Patients with Acquired Immunodeficiency Syndrome
摘要
Abstract
Objective To explore the prognostic factors of disseminated Penicilliosis Marneffei( DPsM )in patients with acquired immunodeficiency syndrome( AIDS ). Methods 124 cases of AIDS complicated with DPsM were evaluated by logistic regression analysis in order to determine independent prognostic factors. Results 124 cases with a mortality rate of 29.84%. In the univariate analysis, 10 variables associated significantly with the prognosis of AIDS complicated with DPsM.These variables included leukocyte count, total bilirubin, the sermn albumin level, blood urea nitrogen, creatinine, CD4 + T lymphocyte count, hepatosplenomegaly, drug abuse or excessive drinking, antiretroviral therapy and using of hormone.Multivariate logistic regression analysis showed the increase of BUN( OR = 0. 584,95% CI 0. 369 -0. 925 )was risk factor related to the mortality of AIDS patients with DPsM, meanwhile, CD4 + T lymphocyte count( OR = 1. 364,95% CI 1. 038 - 1. 792 )and antiretroviral therapy( OR = 17.084,95% CI 5.297 -71. 668 )provided protective effect. Conclusion The increase of BUN is the risk factors contributing to the poor prognosis of AIDS patients with DPsM, while CD4 + T lymphocyte count or antiretroviral therapy can reduce the mortality and improve the prognosis.关键词
艾滋病/马尔尼菲青霉菌病/预后因素/回归分析Key words
Acquired immunodeficiency syndrome/Penicilliosis marneffei/Prognostic factor/Regression analysis分类
医药卫生引用本文复制引用
姚钦江,梁欣,马卫国,韦良宏,黎灿,黄自群,黄丽静,王广银..艾滋病合并播散性马尔尼菲青霉菌病预后因素分析[J].广西医学,2011,33(5):533-535,3.基金项目
广西医药卫生科学研究基金资助项目(Z2009235) （Z2009235）
广西钦州市科学研究与技术开发计划项目(20101904) （20101904）
