中国中医药信息杂志2011，Vol.18Issue(3)：49-51,3.DOI:10.3969/j.issn.1005-5304.2011.03.018
辛热示例药对正常大鼠基础代谢及内分泌系统的影响
Effect of Pungent-hot Herb on Basal Metabolism and Endocrine System of Normal Rats
摘要
Abstract
Objective To observe the effects of pungent-hot herb decoction of Radix Aconiti Lateralis Preparata, Cortex Cinnamomi Aconite and Rhizoma Zingiberis on basal metabolism and endocrine system of normal rats. Methods SD rats were divided into two groups. The control group was given 4 mL water and the experimental group was given 4 mL pungent-hot decoction by intragastric admirustration for consecutive 9 weeks. Blood was collected from abdominal vein after anesthetized by intraperitoneal injection of 2％ pentobarbital sodium. Serum GLU, TG, TC, TP, ALB, LDH, LAC levels were detected by automatic biochemical analyzer, and serum E2, T, COR, T3, T4, TSH levels were determined by radio-immunity. Results Serum TG, TC, TP, LAC, LDH levels were significantly increased in experimental group, while COR, E2, T, T3 levels were significantly lowered. The other parameters were not changed significantly. Conclusion The basal metabolism rate was accelerated and the endocrine system was inhibited after given pungent-hot herb decoction for 9 weeks. These changes may be associated with expression characteristics of pungent-hot herbs, however, the specific mechanism needs further study.关键词
辛热药/附子/肉桂/干姜/基础代谢/内分泌系统/药性表达/大鼠分类
医药卫生引用本文复制引用
李连珍,刘小青,崔一然,张冰..辛热示例药对正常大鼠基础代谢及内分泌系统的影响[J].中国中医药信息杂志,2011,18(3):49-51,3.基金项目
国家重点基础研究发展计划(2007CB512605) （2007CB512605）
