北京大学学报（医学版）2011，Vol.43Issue(2)：272-275,4.DOI:10.3969/j.issn.1671-167X.2011.02.021
放射性粒子组织间植入治疗口腔颌面-头颈部腺源性恶性肿瘤近期疗效分析
Radioactivity seeds interstitial brachytherapy treating malignant salivary gland tumors
张杰 1郑磊 1黄明伟 1刘树铭 1贾凌飞 1石妍 1俞光岩 1张建国1
作者信息
- 1. 北京大学口腔医学院·口腔医院颌面外科,北京,100081
- 折叠
摘要
Abstract
Objective: To detect the efficacy of 125Ⅰ radioactive seeds implanting treating malignant salivary gland tumors. Methods: Forty-three patients with malignant salivary gland tumors of head neck were treated with 125Ⅰ radioactivity seeds interstitial brachytherapy at Peking University Stomatologic Hospital between 2001 and 2008. These patients were implanted with 125Ⅰ radioactivity seeds with the dosage of 120 to 160 Gy. The treatment response, local control rate and survival rate were evaluated and the adverse events observed. Results : Twenty-nine patients had complete remission ( CR) of their tumors, and seven patients partial remission ( PR) . The response rate was 83. 7％ . The patients were followed up for 8 to 48 months ( median 21 months). The local control rate was 79％ , and total survival rate 76. 7％ . No serious side radiotherapeutic effect was observed. Conclusion: Radioactivity seeds interstitial brachytherapy is an effective form of treatment for patients with unresectable malignant salivary gland tumors.关键词
头颈部肿瘤/近距离放射疗法/治疗结果分类
医药卫生引用本文复制引用
张杰,郑磊,黄明伟,刘树铭,贾凌飞,石妍,俞光岩,张建国..放射性粒子组织间植入治疗口腔颌面-头颈部腺源性恶性肿瘤近期疗效分析[J].北京大学学报（医学版）,2011,43(2):272-275,4.
