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AS炎性信号通路与中医药干预

马悦颖 刘建勋

中国药理学通报2011,Vol.27Issue(6):745-747,3.
中国药理学通报2011,Vol.27Issue(6):745-747,3.DOI:10.3969/j.issn.1001-1978.2011.06.002

AS炎性信号通路与中医药干预

Progression on inflammatory signaling pathway of atherosclerosis and the intervention of TCM

马悦颖 1刘建勋1

作者信息

  • 1. 中国中医科学院西苑医院实验研究中心,北京,100091
  • 折叠

摘要

Abstract

Atherosclerosis ( AS ) is now understood to be a disease characterized by chronic inflammation caused by blood vessel endothelium lesion. In this review, we highlight the role of inflammatory signaling pathway including intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 ( VCAM-1 ), nuclear factor kappaB ( NF-κB ) and peroxisome proliferators activated receptor γ ( PPARγ ) in atherosclerosis.Moreover, this review also focuses on recent progresses of traditional Chinese medicine ( TCM ) in preventing or treating atherosclerosis.

关键词

动脉粥样硬化/ICAM-1/VCAM-1/NF-κB/PPARγ/中医药

分类

医药卫生

引用本文复制引用

马悦颖,刘建勋..AS炎性信号通路与中医药干预[J].中国药理学通报,2011,27(6):745-747,3.

基金项目

国家自然科学基金资助项目(No 30830118) (No 30830118)

国家科技重大专项,重大新药创制资助项目(No 2009zx09301-005 ()

2009zx0930 3-003) ()

中国药理学通报

OA北大核心CSCDCSTPCD

1001-1978

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