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细菌天然密度感应系统抑制剂的研究进展

李月恒

国际口腔医学杂志2011,Vol.38Issue(2):246-248,3.
国际口腔医学杂志2011,Vol.38Issue(2):246-248,3.DOI:10.3969/j.issn.1673-5749.2011.02.032

细菌天然密度感应系统抑制剂的研究进展

Research progress on natural quorum sensing system inhibitors in bacterial

李月恒1

作者信息

  • 1. 重庆医科大学附属口腔医院牙体牙髓病科,重庆,400015
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摘要

Abstract

The ability of bacteria to sense and respond to population density is termed cell-to-cell commumcation or quorum sensing system (QSS). And many bacterial physiological functions such as biofilm formation and virulence are regulated by QSS. QSS is seemed to be a novel target for some anfimicrobial drugs which can block reception of the cognate QSS signals in vivo and finally inducing chemical attenuation of pathogens. Recently,some researchers have found that some natural substances can interfere with the cycle of QSS. The natural inhibitors of QSS will be introduced in this view.

关键词

密度感应系统/抑制剂/天然物质/自身诱导分子

Key words

quorum sensing system/ inhibitors/ natural substance/ autoinducer

分类

医药卫生

引用本文复制引用

李月恒..细菌天然密度感应系统抑制剂的研究进展[J].国际口腔医学杂志,2011,38(2):246-248,3.

基金项目

重庆市卫生局科研课题基金资助项目(2008-2-249) (2008-2-249)

重庆市卫生局中医药科研计划基金资助项目(2010-2-64) (2010-2-64)

国际口腔医学杂志

OACSTPCD

1673-5749

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