国际口腔医学杂志2011,Vol.38Issue(2):246-248,3.DOI:10.3969/j.issn.1673-5749.2011.02.032
细菌天然密度感应系统抑制剂的研究进展
Research progress on natural quorum sensing system inhibitors in bacterial
摘要
Abstract
The ability of bacteria to sense and respond to population density is termed cell-to-cell commumcation or quorum sensing system (QSS). And many bacterial physiological functions such as biofilm formation and virulence are regulated by QSS. QSS is seemed to be a novel target for some anfimicrobial drugs which can block reception of the cognate QSS signals in vivo and finally inducing chemical attenuation of pathogens. Recently,some researchers have found that some natural substances can interfere with the cycle of QSS. The natural inhibitors of QSS will be introduced in this view.关键词
密度感应系统/抑制剂/天然物质/自身诱导分子Key words
quorum sensing system/ inhibitors/ natural substance/ autoinducer分类
医药卫生引用本文复制引用
李月恒..细菌天然密度感应系统抑制剂的研究进展[J].国际口腔医学杂志,2011,38(2):246-248,3.基金项目
重庆市卫生局科研课题基金资助项目(2008-2-249) (2008-2-249)
重庆市卫生局中医药科研计划基金资助项目(2010-2-64) (2010-2-64)