国际口腔医学杂志2011，Vol.38Issue(2)：177-180,4.DOI:10.3969/j.issn.1673-5749.2011.02.014
β-防御素的抗肿瘤活性及其与口腔癌相关性的研究进展
Research progress on the anti-tumor activity of beta-defensins and its correlation with oral carcinoma
摘要
Abstract
Defensins are a class of cationic peptides which is widely found in plants and animals, and are a representative sub-clan of antimicrobial peptides family (Antimicrobial peptides are a kind of short-chain poptide of broad-spectntm antimicrobial effects) and a very conservative host defense molecules. So far, a variety of defensins have been found. Human beta defensin (hBD) play an important role in these dofensins, and have a strong bactericidal activity, chemotactic activity, regulatory function of phagocytic cells and acquired immune etc. In addition, several researches also found that hBD have an anti-tumor activity, and are closely related with oral carcinoma. Therefore, hBD may provide a new strategy for the prevention and treatment of the tumor.关键词
β-防御素/抗肿瘤活性/口腔癌Key words
beta-defensin/ anti-tumor activity/ oral carcinoma分类
生物科学引用本文复制引用
李艳忠,但红霞,刘娜..β-防御素的抗肿瘤活性及其与口腔癌相关性的研究进展[J].国际口腔医学杂志,2011,38(2):177-180,4.基金项目
国家自然科学基金资助项目(30772424、30930100、81072218) （30772424、30930100、81072218）
