中山大学学报（医学科学版）2011，Vol.32Issue(2)：141-145,154,6.
干细胞niche与心肌细胞分化的调控机制研究
Regulatory Mechanism of Niche on Stem Cells Differentiation to Cardiomyocytes
摘要
Abstract
Stem cells are the special cells of self-renewal and differentiation potential. Recent studies found that the biological behaviors of stem cells are highly dependent on their microenvironment (niche). There are two roles of niche on stem cells: the direct effects between cell contacts, and the indirect effects such as matrix and cytokines which involve in several signal transduction pathways and their cross-talks. Here, we mainly describe the effects of bone marrow niche on mesenchymal stem cells (SMC), and the regulatory mechanisms of MSC differentiation into myocardial cells.关键词
干细胞/微环境/心肌细胞/细胞分化分类
医药卫生引用本文复制引用
余细勇..干细胞niche与心肌细胞分化的调控机制研究[J].中山大学学报（医学科学版）,2011,32(2):141-145,154,6.基金项目
国家自然科学基金(30772142,81070103) （30772142,81070103）
