华西口腔医学杂志2011，Vol.29Issue(2)：164-167,4.DOI:10.3969/j.issn.1000-1182.2011.02.015
颌面部淋巴结反应性增生的临床与病理研究
Clinicopathologic study on reactive hyperplasia of lymph nodes in maxillofacial regions
李志刚 1王霄 1潘向勇 1李敏 2邹士琦1
作者信息
- 1. 北京大学第三医院,口腔科
- 2. 北京大学基础医学院病理学系,北京100191
- 折叠
摘要
Abstract
Objective To investigate the clinicopatholigic features of reactive hyperplasia of lymph nodes in maxillofacial regions.Methods Thirty-two patients with lymph node reactive hyperplasia(LRH) were analyzed clinicopathologically including pathomorphologic manifestation and immunohistochemical expression.Results Histopathology of 32 patients showed significant hyperplasia in folliculus lymphaticus, marginal zone lymph, paracortical area lymph,and seldom mixed hyperplasia.Immunohistochemical study showed that the hyperplastic lymphocytes were mainly composed of CD20 positive B cells positive in 23 cases (72％), CD3 positive T cell in 7 cases (22％), CD20 positive T cell and CD3 positive B cell partially as well as histiocytes in 2 cases(6％).Atypical hyperplasia was found in 10 cases.Conclusion Hyperplastic lymphocytes in LRH of maxillofacial regions are mainly composed of B cells.Malignant transformation may occur in these patients with atypical hyperplasia.Regularity follow up is necessary for these patients.关键词
淋巴结/反应性增生/颌面部/免疫组织化学Key words
lymph node/ reactive hyperplasia/ maxillofacial region/ immunohistochemistry分类
医药卫生引用本文复制引用
李志刚,王霄,潘向勇,李敏,邹士琦..颌面部淋巴结反应性增生的临床与病理研究[J].华西口腔医学杂志,2011,29(2):164-167,4.
