重症肺炎支原体肺炎患儿肺泡灌洗液中Th1/Th2细胞免疫应答状况的研究OA北大核心CSCDCSTPCD
Th1/Th2 immune response in bronchoalveolar lavage fluid in children with severe Mycoplasma pneumoniae pneumonia
目的:检测重症肺炎支原体肺炎(MPP)患儿肺泡灌洗液(BALF)和血清中干扰素-γ(IFN-γ)、白细胞介素-4(IL-4),研究Th1/TH2细胞免疫应答的状况及意义,并评价BALF中细胞因子检测在MPP诊治中的临床价值.方法:采用双抗体夹心ELISA检测25例重症MPP患儿BALF和血清中IL-4及IFN-γ的浓度,并设支气管异物组(25例)和MPP轻症组(25例)作为对照.结果:重症MPP患儿BALF中IL-4和IFN-γ水平及IL-4/I…查看全部>>
Objective To study the status of Th1/Th2 immune response and the value of the detection of cytokines in bronchoalveolar lavage fluids (BALF) by examining the levels of IFN-γ and IL-4 in BALF and serum in children with severe Mycoplasma pneumonia (MPP).Methods The levels of IFN-γ and IL-4 in BALF and serum were measured using ELISA in 25 children with severe MPP, 25 children with mild MPP and 25 children with foreign body in bronchus.Results The levels of IL-…查看全部>>
康妍萌;丁明杰;韩玉玲;王世富;马香;李华
山东大学齐鲁儿童医院呼吸科,山东,济南,250022山东大学齐鲁儿童医院呼吸科,山东,济南,250022山东大学齐鲁儿童医院呼吸科,山东,济南,250022山东大学齐鲁儿童医院检验科,山东,济南,250022山东大学齐鲁儿童医院呼吸科,山东,济南,250022山东大学齐鲁儿童医院呼吸科,山东,济南,250022
医药卫生
重症肺炎支原体肺炎肺泡灌洗液Th1/Th2儿童
《中国当代儿科杂志》 2011 (3)
188-190,3
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