中国临床药理学杂志2011，Vol.27Issue(3)：225-228,4.
本院呼吸内科住院患者抗菌药物使用情况调查
Surveillance of antimicrobial prescription for inpatients with respiratory diseases in a hospital
季闽春 1沈晓英 1金蕾 1杨耀芳1
作者信息
- 1. 复旦大学附属上海市第五人民医院药剂科,上海,200240
- 折叠
摘要
Abstract
Objective To collect some information on antimicrobial prescription for inpatients with respiratory diseases in a hospital and to improve the appropriateness of prescriptions.Methods We retrospectively reviewed records of inpatients discharged between April 1st and August 31 st 2006 at the respiratory department.Recorded information about gender, age of patients, diagnosis, history of drug allergy, antimicrobial dosage, regimen, cost and evaluated the appropriateness of prescriptions.Results A total of two hundred and twenty cases were assessed, 136 were men and 84 were women, aged from 15 to 93 years old.The prima ry diseases were community - acquired pneumonia, chronic obstructive disease and acute bronchitis.As many as 86.4％ of patients had sputum sample cultured for specific pathogens, and 35.6％ of them got positive results.Fluoroquinolones, cephalosporins and penicillins combinations were the most frequently used antibiotics.One hundred and eighty - eight of patients were administrated by intravenous, and 39 of them were switched from intravenous to oral therapy.There were some inappropriate of drug dose, interval and solvents.Conclusion Physicians can compliance with the guidelines to improve management of respiratory diseases,but they should individualize the regimen in accordance with the PK/PD parameters of antibiotic agents.关键词
呼吸系统疾病/抗菌药物/处方合理性分类
医药卫生引用本文复制引用
季闽春,沈晓英,金蕾,杨耀芳..本院呼吸内科住院患者抗菌药物使用情况调查[J].中国临床药理学杂志,2011,27(3):225-228,4.
