摘要
Abstract
Aim: To investigate the expression of Livin and Smac in the endometriosis and the correlationship between them. Methods:The expression levels of Livin and Smac protein in ectopic endometrium (group A), eutopic endometrium (group B) and normal endometrium (group C )( n = 30)were detected by SP method. Results: ①The expression of Livin in Group A, B and C were ( 142.55 ± 36.27),( 141.69 ±26.61 ),( 113.26 ± 10.22) ,the expression of Smac in the 3 groups were (114.76 ± 10.68 ), ( 112.41 ± 8.84 ), ( 143.73 ± 10.83 ), and there were differences among 3 groups ( F =16.465 and 14.708 ,P ＜0.05). ②In Group A and B, the expression of Livin and Smac were negative related( r = -0.552 and -0.397,P ＜0.001 ). ③The expression of Smac in Group A between the proliferative phase and the secretory phase were (118.23 ±24.69) ,(124.07 4±21.31), and there was no significant difference(t= 0.645, P =0.510) ,in Group C were ( 150.93 ± 3.04 ), ( 159.18 ± 13.20), and there was significant difference( t = 1. 982, P = 0.043 ). The expression of Livin during the proliferative phase in Group A and C were (141.63 ± 36.69,112.01 ± 8.93), and during the secretory phase were( 143.75 ±37.16,115.13 ± 12.07) (t =0.178 and 0.794,P ＞0.05). Conclusion:Livin and Smac may play an important role in the pathogenisis of endometriosis.关键词
子宫内膜异位症/Livin/SmacKey words
endometriosis /Livin /Smac分类
医药卫生
