中国药房2011，Vol.22Issue(15)：1419-1422,4.
感咳双清胶囊治疗急性上呼吸道感染的系统评价
Ganke Shuangqing Capsule for Acute Upper Respiratory Tract Infection:A Systematic Review
罗敏 1华鹏 2唐尧1
作者信息
- 1. 四川大学华西医院药剂科,成都市,610041
- 2. 云南省第三人民医院药剂科,昆明市,650011
- 折叠
摘要
Abstract
OBJECTIVE: To evaluate the clinical efficacy and safety of Ganke shuangqing capsule for acute upper respiratory tract infection.METHODS: All randomized controlled trails (RCTs) of Ganke shuangqing capsule for acute upper respiratory tract infection were searched from CNKI, VIP, CBM, MEDLINE, EMBASE, Cochrane Library.The quality evaluation of the included studies referred to the Cochrane systematic reviews handbook 5.0.1, and RevMan 5.0 software was used for data analysis.RESULTS: 6 RCTs involving 1 194 patients with acute upper respiratory tract infection were included.Meta-analyses showed that in children the total effective rate of treatment group A1 was better than control group A2, there was statistically significant difference [RR= 1.15,95％ CI( 1.08,1.22)]in adults the total effective rate of treatment group A1 was better than control group A2, there was statistically significant difference [RR=1.18, 95％ CI (1.09, 1.28)]There was no significant difference in total effective rate between treatment group B1 and control group B2[RR= 1.02,95 ％ CI (0.94, 1.12)].The descriptive analysis was used because of clinical heterogeneity of main symptoms remission rate.CONCLUSION: In children, Ganke shuangqing capsule is better than ribavirin in the treatment of acute upper respiratory tract infection; In adults, total effective rate and main symptoms remission rate of Ganke shuangqing capsule for acute upper respiratory tract infection was better than or not inferior to ribavirin and Qinggan chuanxinlian tablets.Large-scale high quality RCTs were required to validate the results.关键词
感咳双清胶囊/急性上呼吸道感染/系统评价分类
医药卫生引用本文复制引用
罗敏,华鹏,唐尧..感咳双清胶囊治疗急性上呼吸道感染的系统评价[J].中国药房,2011,22(15):1419-1422,4.
