南方医科大学学报2011，Vol.31Issue(3)：564-566,3.
格列美脲联合二甲双胍短期内强化治疗对初诊2型糖尿病疗效的观察
Effect of short-term intensive therapy with glimepiride and metformin in newly diagnosed type 2 diabetic patients
汪敏 1高方 2薛耀明 2韩亚娟 2符霞军 2何飞英2
作者信息
- 1. 广州市胸科医院内分泌合并结核病科,广东广州,510095
- 2. 南方医科大学南方医院内分泌代谢科,广东广州,510515
- 折叠
摘要
Abstract
To evaluate the effect of short-term intensive therapy on blood glucose control, β-cell function, and blood lipid levels in newly diagnosed type 2 diabetic patients. Methods Out-patients with newly diagnosed type 2 diabetic patients were enrolled for intensive treatment with sulfonylureas and metformin for 12 weeks, and the therapeutic effect was evaluated. Results After the intensive treatment, FPG, 2 hPG, and HbAlc decreased significantly (P<0.01); HOMA-IR decreased and HOMA-B increased significantly (P<0.01), and TG, CHOL, LDL decreased significantly (P<0.01) after the treatment. Conclusion Short-term intensive treatment with glimepiride combined with metformin is safe and effective in newly diagnosed type 2 diabetic patients with HbAlc>9%.关键词
2型糖尿病/强化治疗/格列美脲/胰岛β细胞功能/血脂Key words
type 2 diabetes mellitus/ intensive therapy/ glimepiride /β-cell fuction/ lipid分类
医药卫生引用本文复制引用
汪敏,高方,薛耀明,韩亚娟,符霞军,何飞英..格列美脲联合二甲双胍短期内强化治疗对初诊2型糖尿病疗效的观察[J].南方医科大学学报,2011,31(3):564-566,3.
