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胃大部切除术后Roux-en-Y吻合对非肥胖2型糖尿病的临床疗效观察

冯超 姚若全 黄飞舟 聂晚频 刘浔阳

南方医科大学学报2011,Vol.31Issue(3):551-553,3.
南方医科大学学报2011,Vol.31Issue(3):551-553,3.

胃大部切除术后Roux-en-Y吻合对非肥胖2型糖尿病的临床疗效观察

Therapeutic effect of subtotal gastrectomy and Roux-en-Y gastrojejunostomy on type 2 diabetes mellitus in non-obese patients

冯超 1姚若全 1黄飞舟 1聂晚频 1刘浔阳1

作者信息

  • 1. 中南大学湘雅三医院普外科,湖南,长沙,410013
  • 折叠

摘要

Abstract

To evaluate the therapeutic effect of Roux-en-Y anastomosis following subtotal gastrectomy on type 2 diabetes mellitus (T2DM) in non-obese patients. Methods We performed a retrospective analysis of 16 non-obese patients with T2DM undergoing Roux-en-Y anastomosis following subtotal gastrectomy for stomach cancer and upper gastrointestinal tract ulcer. Results All the patients were followed up for 6 months after the surgery. Roux-en-Y gastrojejunostomy significantly lowered the levels of fasting plasma glucose (FPG), 2 h postprandial plasma glucose (2hPG), and glycated hemoglobin (HbAlc) (P0.05). Of these patients, 8 (50%) achieved adequate glycemic control without antidiabetic medication and 5 (31.25% ) showed obvious improvement. The total effectiveness rate of the surgery was 81.25%. Conclusion Roux-en-Y gastrectomy can effectively ameliorate the diabetic symptoms and might serve as a new treatment option for T2DM in non-obese patients.

关键词

胃大部分切除术/Roux-en-Y吻合/2型糖尿病

Key words

subtotal gastrectomy/ Roux-en-Y gastrojejunostomy/ type 2 diabetes mellitus

分类

医药卫生

引用本文复制引用

冯超,姚若全,黄飞舟,聂晚频,刘浔阳..胃大部切除术后Roux-en-Y吻合对非肥胖2型糖尿病的临床疗效观察[J].南方医科大学学报,2011,31(3):551-553,3.

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