实验动物与比较医学2011，Vol.31Issue(2)：115-119,133,6.DOI:10.3969/j.issn.1674-5817.2011.02.010
双橘颗粒药效学实验研究
The Treatment of Shuangju Particles on Hyperplasia of Mammary Gland in Rat and Rabbit
摘要
Abstract
Objective To observe the therapeutic effects of Shuangju Particles on experimental hyperplasia of mammary glands in rat and rabbit. Method The model of mammary gland hyperplasia was established by injection of estradiol benzoatics in this experiment, To observe the treatment of shuangju particles on mammary gland hyperplasia in rat and rabbit. Result The Shuangju particles can inhibit mammary enlargement caused by estrogen, reduce the level of E2 in serum of rats and rabbit with mammary gland hyperplasia, increase the content of progesterone, reduce the number of lobular, acinar,the cell proliferative layer and the degree of mammary duct expansion. Meanwhile, the experiment of egg white induced foot swelling showed that it also has significant anti-inflammatory effect. Conclusion Shuangju Particles has preventive and therapeutic effects on experimental hyperplasia of mammary glands in rats and rabbit, and it may be used to treat disease of mammary gland hyperplasia in clinical.关键词
双橘颗粒/乳腺增生/大鼠/兔分类
生物科学引用本文复制引用
郭晟,郑国安,李良..双橘颗粒药效学实验研究[J].实验动物与比较医学,2011,31(2):115-119,133,6.
