河北医学2011，Vol.17Issue(3)：334-336,3.DOI:10.3969/j.issn.1006-6233.2011.03.019
甲磺酸伊马替尼治疗晚期胃肠间质瘤的临床疗效观察
Clinical Efficacy on Imatinib Mesylate Treatment for Patients with Advanced Gastrointestinal Stromal Tumors
陈杰 1钟克力 1郭春华 1夏利刚 1潘凯1
作者信息
- 1. 广东省深圳市人民医院胃肠外科,广东,深圳,518020
- 折叠
摘要
Abstract
Objective: To evaluate the efficacy and toxicity of imatinib mesylate in the treatment of advanced gastrointestinal stromal tumors. Method:A total of 25 cases with advanced gastrointestinal stromal tumors that all proven by pathology were received imatinib mesylate at doses of 400mg/d, from Oct. 2006 to Oct. 2010. Result: All cases were followed up. None had complete response , 13 cases achieved partial response ( PR ), 8 cases achieved stable disease ( SD) and 4 had progression disease ( PD ). The overall survival rates at 1 and 2 year was 100％ and 96％ respectively. 25 patients were valuable for the toxicity assessment according to the WHO standard. Conclusion: Imatinib mesylate is a safe and efficacious drug used for the patients with advanced gastrointestinal stromal tumors. Only mild adverse reactions occur and toxicity is acceptable.关键词
胃肠间质瘤/甲磺酸伊马替尼/晚期Key words
Gastrointestinal stromal tumors/ Imatinib mesylate/ Advanced引用本文复制引用
陈杰,钟克力,郭春华,夏利刚,潘凯..甲磺酸伊马替尼治疗晚期胃肠间质瘤的临床疗效观察[J].河北医学,2011,17(3):334-336,3.
