同济大学学报（医学版）2011，Vol.32Issue(2)：84-88,5.DOI:10.3969/j.issn.1008-0392.2011.02.021
重症监护病房下呼吸道感染病原菌分布和耐药性分析
Analysis of distribution and drug resistance of pathogens of lower respiratory tract infections in ICU
毛彦华 1刘锦铭 2陈慧萍 3王暖3
作者信息
- 1. 同济大学附属肺科医院感染管理科,上海,200433
- 2. 同济大学附属肺科医院呼吸科,上海,200433
- 3. 同济大学附属肺科医院检验科,上海,200433
- 折叠
摘要
Abstract
Objective To analyze the bacterial distribution and resistance of pathogens of lower respiratory tract infections in intensive care unit (ICU) from 2007 to 2009 to provide basis for infection control and the better administration of antibiotics. Methods Mean inhibitory concentration (MIC) tests were conducted to detect the antimicrobial sensitivity of 266 bacterial strains. WHONET5.4 was applied to analyze the bacterial distribution and resistance data. Results The main pathogens were Gram-negative strains accounting for 66.54％. Acinetobacter baumannii (30. 83％ ), Pseudomonas aeruginosa ( 13.53％ ) and Klebsiella pneumoniae (8.65％)were the most common Gram-negative isolates. 16.92％ of total isolates were Gram-positive strains,of which 11.65％ were Staphylococus aureus. The percentage offungi was 16.54％. The resistance of Gramnegative non-fermenting bacteria to most antibiotics (including Imipenem) was severe. The resistant rates of Staphylococus aureus to oxacillin was up to 80％. Conclusion In view of the increasing multidrug resistance of Gram-negative non-fermenting bacteria and Staphylococus aureus in ICU, rational administration of antibiotics and iatrogenic infection prevention measures should receive great attention.关键词
重症监护病房/下呼吸道感染/病原菌/耐药性分类
医药卫生引用本文复制引用
毛彦华,刘锦铭,陈慧萍,王暖..重症监护病房下呼吸道感染病原菌分布和耐药性分析[J].同济大学学报（医学版）,2011,32(2):84-88,5.
