中国美容医学2011，Vol.20Issue(z1)：341-342,2.
卡培他滨联合奥沙利铂治疗晚期胃癌的疗效观察
Efficacy of Xeloda Combined with Oxaliplatin for Advanced Gastric Cancer
云辉1
作者信息
- 1. 解放军第187中心医院,河南,海口,571159
- 折叠
摘要
Abstract
Objectice: To investigate the efficacy and toxicity of xeloda combined with oxaliplatin(XELOX) in the treatment of advanced gastric cancer. Methods: Data of patients with advanced gastric cancer treated with XELOX(n=49) from january 2005 to june 2009 were retrospectively analysed and compared with 5-Fusoxaliplptin and leucovorin combination chemotherapy(OLF, n= 58). Reslllts: the overall response rate was 34.7 ％ and time to disease progression (TTP) was 6.2 months in XELOX group; the corresponding values were 32.7％ and 5.9 months respectively in OLF group, with no signficant differences between the two groups. The main toxicities were diarrhea, nausea, vomit, myelosuppression and liver function injury in both group, the diferences between the two groups were not significant. The incidence of hand-foot syndrome in XELOX group was significantly higher than that in OLF group, but usually was sllght(grade Ⅰ-Ⅱ). Conclusion: The efectiveness of XELOX regimen is the same as that of OLF regimen for advanced gastric cancer and the toxici ties are tolerable. But XELOX regimen is more convenient and superior to OLF regimen for recurent patients.关键词
卡培他滨/奥沙利铂/晚期胃癌分类
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云辉..卡培他滨联合奥沙利铂治疗晚期胃癌的疗效观察[J].中国美容医学,2011,20(z1):341-342,2.
