军医进修学院学报2011,Vol.32Issue(4):378-380,3.
大鼠椎间盘损伤模型的建立及椎间盘内CD34的改变
Establishment of rat intervertebral dick injury model and change of CD34 in intervertebral dick
隰建成 1白一冰 1侯树勋 2贺占国3
作者信息
- 1. 解放军第309医院,骨科,北京,100091
- 2. 解放军总医院304临床部,骨科,北京,100037
- 3. 白求恩国际和平医院,风湿免疫科,石家庄,050000
- 折叠
摘要
Abstract
Objective To establish the rat model of low back pain due to intervertebral disc injury and observe the change of CD34 in intervertebral discs. Methods Ninety-six male SD rats were randomly divided into control group (sham operation group), first operation group and second operation group. Expression of CD34 in injured L6-7 intervertebral discs was detected with immunohistochernical methods at different time points. Results The rat model of low back pain due to intervertebral disc injury was successfully established. Sporadic CD34 positive cells were observed in the inner fibrous rings of intervertebral discs after operation. Conclusion CD34 is expressed in intervertebral discs of rats with low back pain due to intervertebral disc injury, indicating the formation of vascular endothelial cells.关键词
椎间盘/模型,动物/CD34Key words
Intervertebral Disk/Models,Animal/CD34分类
医药卫生引用本文复制引用
隰建成,白一冰,侯树勋,贺占国..大鼠椎间盘损伤模型的建立及椎间盘内CD34的改变[J].军医进修学院学报,2011,32(4):378-380,3.