浙江医学2011，Vol.33Issue(5)：669-672,4.
股骨头坏死特殊结构的组织学观察及其临床意义
Histopathological features of special structures in osteonecrosis of femoral head and clinical significance
摘要
Abstract
Objective To investigate the histopathological features of special structures in osteonecrosis of femoral heads (ONFH) and its clinical significance.Methods Thirteen specimens of femoral heads were randomly taken from 73 femoral heads with necrosis for total hip replacement, including 5 cases in stage Ⅲ, 8 cases in stage Ⅳ according to the ARCO stage system.Seven cases were induced by steroid overuse (5 men and 2 women), 6 cases were induced by alcohol abuse (6 men).The patients were aged 30 to 72y with average of 45.5.Two specimens of femoral heads with fresh femoral neck fracture were served as controls.The tissue sections were made from 1) weight- bearing cartilage, 2) bone tissues from the center ofnecrosis under cartilage, 3)renovating band and 4)the normal head- neck area, and stained by HE and improved Masson methods.The histopathological features were observed with light microscopy focusing on the cystic degeneration, repairing band and mushroom- like hyperplasia.Results The cystic degeneration, repairing band, mushroom- like hyperplasia had different appearance and they were the special structure in osteonecrosis ofthe femoral head.Conclusion The histopathologic characteristics of special structures in ONFH are of use in understanding of the features of ONFH and the selection of therapeutic schedule.关键词
股骨头坏死/组织病理学/囊变/修复带/蘑菇状改变/光镜观察Key words
ONFH(osteonecrosis of the femoral head) / Histopathology / Cystic / degeneration / Repairing band /Mushroom hyperplasia / Light microscopy引用本文复制引用
崔永锋,朱宝华,管功奎,肖鲁伟,童培建..股骨头坏死特殊结构的组织学观察及其临床意义[J].浙江医学,2011,33(5):669-672,4.基金项目
中国博士后科学基金资助项目(20080431334) （20080431334）
