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深圳儿童医院2010年常见病原菌分布及耐药性调查

胡瑛 文飞球 钟春梅 王红梅

儿科药学杂志2011,Vol.17Issue(3):43-46,4.
儿科药学杂志2011,Vol.17Issue(3):43-46,4.

深圳儿童医院2010年常见病原菌分布及耐药性调查

Antibiotic-resistance and Distribution of Nosocomial Infection Pathogens among Children Patients in Shenzhen Children's Hospital

胡瑛 1文飞球 1钟春梅 1王红梅1

作者信息

  • 1. 广东省深圳市儿童医院,广东深圳,518026
  • 折叠

摘要

Abstract

Objective: To understand the main pathogens of nosocomial infection and analyze its distribution as well as its drug resistance, then to find an effective way to deal with such pathogens. Methods: Made a retrospective investigation on the clinical data of hospitalized patients who stayed in Shenzhen Children's Hospital during January to December 2010. Results: It appeared 3,629 cases, among which there were 2,493 Gram-negative strains (took up 68.7% ), while Gram-positive were 1,136 strains ( took up 31.3% ). The main pathogens were Klebsiella pnenmoniae (22.7%), Escherichia coli (20.4%), and Acinetobacter banmanii (10.7%) among gram negative bacteria. The ESBLs-prodncing rates of Escherichia coli and Klebsiella pnenmoniae were 51.7% and 41.3% while MRSA in gram positive coccus was 15.5%. Gram-negative pathogens showed high rates of chug-sensitivity on carbapenem and enzyme inhibitors, and gram-positive pathogens showed 93.5% drug resistance to penicillin. No resistant strains to carbapenem, rifampin, ansamycins, fosfomycin and glycopeptides were detected. Conclusions: The main infection in ous hospital was lower respiratory tract ones, carbapenem and vancomycin remain highly active against Enterobacteriaceae and Staphylococci which were the main pathogens in our hospital.

关键词

院内感染/病原菌/耐药性

Key words

Nosoeomial infection/ Pathogens/ Drug resistance

分类

医药卫生

引用本文复制引用

胡瑛,文飞球,钟春梅,王红梅..深圳儿童医院2010年常见病原菌分布及耐药性调查[J].儿科药学杂志,2011,17(3):43-46,4.

儿科药学杂志

OACSTPCD

1672-108X

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